YGL086W

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Systematic name YGL086W
Gene name MAD1
Aliases
Feature type ORF, Verified
Coordinates Chr VII:347122..349371
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Description of YGL086W: Coiled-coil protein involved in the spindle-assembly checkpoint; phosphorylated by Mps1p upon checkpoint activation which leads to inhibition of the activity of the anaphase promoting complex; forms a complex with Mad2p[1][2]



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References

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  1. Hardwick KG and Murray AW (1995) Mad1p, a phosphoprotein component of the spindle assembly checkpoint in budding yeast. J Cell Biol 131(3):709-20 SGD PMID 7593191
  2. Hardwick KG, et al. (1996) Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption. Science 273(5277):953-6 SGD PMID 8688079

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