YFL045C

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Systematic name YFL045C
Gene name SEC53
Aliases ALG4
Feature type ORF, Verified
Coordinates Chr VI:44392..43628
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Description of YFL045C: Phosphomannomutase, involved in synthesis of GDP-mannose and dolichol-phosphate-mannose; required for folding and glycosylation of secretory proteins in the ER lumen[1][2]



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References

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  1. Feldman RI, et al. (1987) Product of SEC53 is required for folding and glycosylation of secretory proteins in the lumen of the yeast endoplasmic reticulum. J Biol Chem 262(19):9332-9 SGD PMID 3298255
  2. Kepes F and Schekman R (1988) The yeast SEC53 gene encodes phosphomannomutase. J Biol Chem 263(19):9155-61 SGD PMID 3288631

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