YOR136W

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Systematic name YOR136W
Gene name IDH2
Aliases
Feature type ORF, Verified
Coordinates Chr XV:580251..581360
Primary SGDID S000005662


Description of YOR136W: Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle[1]




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Protein Details

Other Protein Details

Other Topic: Regulated by the diauxic shift (glycerol)

Apart form the overall increase in mitochondrial protein mass after the diauxic shift this protein remains unchanged after the diauxic shift. [2] [3]





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References

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  1. Cupp JR and McAlister-Henn L (1991) NAD(+)-dependent isocitrate dehydrogenase. Cloning, nucleotide sequence, and disruption of the IDH2 gene from Saccharomyces cerevisiae. J Biol Chem 266(33):22199-205 SGD PMID 1939242
  2. Ohlmeier S, et al. (2004) The yeast mitochondrial proteome, a study of fermentative and respiratory growth. J Biol Chem 279(6):3956-79 SGD PMID 14597615
  3. submitted by Steffen Ohlmeier on 2004-04-08

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