YOL027C
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| Systematic name | YOL027C |
| Gene name | MDM38 |
| Aliases | MKH1 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:273725..272004 |
| Primary SGDID | S000005387 |
Description of YOL027C: Mitochondrial inner membrane protein, involved in membrane integration of a subset of mitochondrial proteins; required for K+/H+ exchange; associates with mitochondrial ribosomes; human ortholog Letm1 implicated in Wolf-Hirschhorn syndrome[1][2][3][4]
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References
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- ↑ Frazier AE, et al. (2006) Mdm38 interacts with ribosomes and is a component of the mitochondrial protein export machinery. J Cell Biol 172(4):553-64 SGD PMID 16476776
- ↑ Froschauer E, et al. (2005) Electroneutral K+/H+ exchange in mitochondrial membrane vesicles involves Yol027/Letm1 proteins. Biochim Biophys Acta 1711(1):41-8 SGD PMID 15904662
- ↑ Nowikovsky K, et al. (2004) The LETM1/YOL027 gene family encodes a factor of the mitochondrial K+ homeostasis with a potential role in the Wolf-Hirschhorn syndrome. J Biol Chem 279(29):30307-15 SGD PMID 15138253
- ↑ Dimmer KS, et al. (2002) Genetic basis of mitochondrial function and morphology in Saccharomyces cerevisiae. Mol Biol Cell 13(3):847-53 SGD PMID 11907266
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