YER147C
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Systematic name | YER147C | |
Gene name | SCC4 | |
Aliases | ||
Feature type | ORF, Verified | |
Coordinates | Chr V:464837..462963 | |
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Description of YER147C: Subunit of cohesin loading factor (Scc2p-Scc4p), a complex required for the loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during double-strand break repair via phosphorylated histone H2AX[1][2][3]
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References
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- ↑ Strom L, et al. (2004) Postreplicative recruitment of cohesin to double-strand breaks is required for DNA repair. Mol Cell 16(6):1003-15 SGD PMID 15610742
- ↑ Unal E, et al. (2004) DNA damage response pathway uses histone modification to assemble a double-strand break-specific cohesin domain. Mol Cell 16(6):991-1002 SGD PMID 15610741
- ↑ Ciosk R, et al. (2000) Cohesin's binding to chromosomes depends on a separate complex consisting of Scc2 and Scc4 proteins. Mol Cell 5(2):243-54 SGD PMID 10882066
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