YDR495C

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Systematic name YDR495C
Gene name VPS3
Aliases PEP6, VPL3, VPT17
Feature type ORF, Verified
Coordinates Chr IV:1441142..1438107
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Description of YDR495C: Cytoplasmic protein required for the sorting and processing of soluble vacuolar proteins, acidification of the vacuolar lumen, and assembly of the vacuolar H+-ATPase[1][2][3]



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References

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  1. Raymond CK, et al. (1990) Molecular analysis of the yeast VPS3 gene and the role of its product in vacuolar protein sorting and vacuolar segregation during the cell cycle. J Cell Biol 111(3):877-92 SGD PMID 2202738
  2. Robinson JS, et al. (1988) Protein sorting in Saccharomyces cerevisiae: isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases. Mol Cell Biol 8(11):4936-48 SGD PMID 3062374
  3. Rothman JH, et al. (1989) Acidification of the lysosome-like vacuole and the vacuolar H+-ATPase are deficient in two yeast mutants that fail to sort vacuolar proteins. J Cell Biol 109(1):93-100 SGD PMID 2526133

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