YBR223C

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Systematic name YBR223C
Gene name TDP1
Aliases
Feature type ORF, Verified
Coordinates Chr II:670292..668658
Primary SGDID S000000427


Description of YBR223C: Tyrosyl-DNA Phosphodiesterase I, hydrolyzes 3'-phosphotyrosyl bonds to generate 3'-phosphate DNA and tyrosine, involved in the repair of DNA lesions created by topoisomerase I[1]




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References

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  1. ↑ Raymond AC, et al. (2005) Substrate specificity of tyrosyl-DNA phosphodiesterase I (Tdp1). J Biol Chem 280(23):22029-35 SGD PMID 15811850

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