S000000116

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Systematic name YBL020W
Gene name RFT1
Aliases
Feature type ORF, Verified
Coordinates Chr II:182404..184128


Description of S000000116: Flippase, essential integral membrane protein that is required for translocation of Man5GlcNac2-PP-Dol from the cytoplasmic side to the lumenal side of the ER membrane; mutation is suppressed by expression human p53 protein[1][2]




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References

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  1. ↑ Helenius J, et al. (2002) Translocation of lipid-linked oligosaccharides across the ER membrane requires Rft1 protein. Nature 415(6870):447-50 SGD PMID 11807558
  2. ↑ Koerte A, et al. (1995) Suppression of the yeast mutation rft1-1 by human p53. J Biol Chem 270(38):22556-64 SGD PMID 7673248

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