YOR075W
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| Systematic name | YOR075W |
| Gene name | UFE1 |
| Aliases | YOR29-26 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:468214..469254 |
Description of YOR075W: t-SNARE required for ER membrane fusion and vesicular traffic, integral membrane protein that constitutes with Sec20p and Use1p the trimeric acceptor for R/v-SNAREs on Golgi-derived vesicles at the ER; part of Dsl1p complex[1][2][3]
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Protein Details
Protein Modification
Modification(s): Phosphorylation
Identified as an efficient substrate of Clb2-Cdk1-as1 in a screen of a proteomic GST-fusion library. [4] [5]
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References
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- ↑ Kraynack BA, et al. (2005) Dsl1p, Tip20p, and the novel Dsl3(Sec39) protein are required for the stability of the Q/t-SNARE complex at the endoplasmic reticulum in yeast. Mol Biol Cell 16(9):3963-77 SGD PMID 15958492
- ↑ Patel SK, et al. (1998) Organelle membrane fusion: a novel function for the syntaxin homolog Ufe1p in ER membrane fusion. Cell 92(5):611-20 SGD PMID 9506516
- ↑ Downing TA and Storms RK (1996) Molecular analysis of UFE1, a Saccharomyces cerevisiae gene essential for spore formation and vegetative growth. Curr Genet 30(5):396-403 SGD PMID 8929391
- ↑ Ubersax JA, et al. (2003) Targets of the cyclin-dependent kinase Cdk1. Nature 425(6960):859-64 SGD PMID 14574415
- ↑ submitted by Jeff Ubersax on 2004-01-29
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