YDR284C

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Systematic name YDR284C
Gene name DPP1
Aliases ZRG1
Feature type ORF, Verified
Coordinates Chr IV:1031415..1030546
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Description of YDR284C: Diacylglycerol pyrophosphate (DGPP) phosphatase, zinc-regulated vacuolar membrane-associated lipid phosphatase, dephosphorylates DGPP to phosphatidate (PA) and Pi, then PA to diacylglycerol; involved in lipid signaling and cell metabolism[1][2][3][4][5][6]



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References

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  1. Han GS, et al. (2001) Regulation of the Saccharomyces cerevisiae DPP1-encoded diacylglycerol pyrophosphate phosphatase by zinc. J Biol Chem 276(13):10126-33 SGD PMID 11139591
  2. Wu WI, et al. (1996) Purification and characterization of diacylglycerol pyrophosphate phosphatase from Saccharomyces cerevisiae. J Biol Chem 271(4):1868-76 SGD PMID 8567632
  3. Furneisen JM and Carman GM (2000) Enzymological properties of the LPP1-encoded lipid phosphatase from Saccharomyces cerevisiae. Biochim Biophys Acta 1484(1):71-82 SGD PMID 10685032
  4. Toke DA, et al. (1999) Mutagenesis of the phosphatase sequence motif in diacylglycerol pyrophosphate phosphatase from Saccharomyces cerevisiae. Biochemistry 38(44):14606-13 SGD PMID 10545184
  5. Toke DA, et al. (1998) Isolation and characterization of the Saccharomyces cerevisiae DPP1 gene encoding diacylglycerol pyrophosphate phosphatase. J Biol Chem 273(6):3278-84 SGD PMID 9452443
  6. Yuan DS (2000) Zinc-regulated genes in Saccharomyces cerevisiae revealed by transposon tagging. Genetics 156(1):45-58 SGD PMID 10978274

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