YOL001W
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| Systematic name | YOL001W |
| Gene name | PHO80 |
| Aliases | AGS3, TUP7, VAC5 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:325250..326131 |
Description of YOL001W: Cyclin, negatively regulates phosphate metabolism; Pho80p-Pho85p (cyclin-CDK complex) phosphorylates Pho4p and Swi5p; deletion of PHO80 leads to aminoglycoside supersensitivity; truncated form of PHO80 affects vacuole inheritance[1][2][3][4]
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References
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- ↑ Measday V, et al. (2000) Interactions between Pho85 cyclin-dependent kinase complexes and the Swi5 transcription factor in budding yeast. Mol Microbiol 35(4):825-34 SGD PMID 10692159
- ↑ Nicolson TA, et al. (1995) A truncated form of the Pho80 cyclin redirects the Pho85 kinase to disrupt vacuole inheritance in S. cerevisiae. J Cell Biol 130(4):835-45 SGD PMID 7642701
- ↑ Wickert S, et al. (1998) A small protein (Ags1p) and the Pho80p-Pho85p kinase complex contribute to aminoglycoside antibiotic resistance of the yeast Saccharomyces cerevisiae. J Bacteriol 180(7):1887-94 SGD PMID 9537389
- ↑ Lenburg ME and O'Shea EK (1996) Signaling phosphate starvation. Trends Biochem Sci 21(10):383-7 SGD PMID 8918192
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