YMR223W

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Systematic name YMR223W
Gene name UBP8
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:716714..718129


Description of YMR223W: Ubiquitin-specific protease that is a component of the SAGA (Spt-Ada-Gcn5-Acetyltransferase) acetylation complex; required for SAGA-mediated deubiquitination of histone H2B[1][2]




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References

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  1. Henry KW, et al. (2003) Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8. Genes Dev 17(21):2648-63 SGD PMID 14563679
  2. Hochstrasser M (1996) Ubiquitin-dependent protein degradation. Annu Rev Genet 30():405-39 SGD PMID 8982460

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