YDR170C

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Systematic name YDR170C
Gene name SEC7
Aliases
Feature type ORF, Verified
Coordinates Chr IV:802219..796190
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Description of YDR170C: Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors involved in proliferation of the Golgi, intra-Golgi transport and ER-to-Golgi transport; found in the cytoplasm and on Golgi-associated coated vesicles[1][2][3]



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References

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  1. Franzusoff A, et al. (1991) Localization of components involved in protein transport and processing through the yeast Golgi apparatus. J Cell Biol 112(1):27-37 SGD PMID 1986005
  2. Wolf J, et al. (1998) An N-end rule destabilization mutant reveals pre-Golgi requirements for Sec7p in yeast membrane traffic. Biochem Biophys Res Commun 243(1):191-8 SGD PMID 9473503
  3. Achstetter T, et al. (1988) SEC7 encodes an unusual, high molecular weight protein required for membrane traffic from the yeast Golgi apparatus. J Biol Chem 263(24):11711-7 SGD PMID 3042778

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