YCR094W
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| Systematic name | YCR094W |
| Gene name | CDC50 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr III:286762..287937 |
| Primary SGDID | S000000690 |
Description of YCR094W: Endosomal protein that interacts with phospholipid flippase Drs2p; interaction with Cdc50p is essential for Drs2p catalytic activity; mutations affect cell polarity and polarized growth; similar to Lem3p; CDC50 has a paralog, YNR048W, that arose from the whole genome duplication[1][2][3][4][5]
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References
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- ↑ Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
- ↑ Lenoir G, et al. (2009) Cdc50p plays a vital role in the ATPase reaction cycle of the putative aminophospholipid transporter drs2p. J Biol Chem 284(27):17956-67 SGD PMID 19411703
- ↑ Misu K, et al. (2003) Cdc50p, a conserved endosomal membrane protein, controls polarized growth in Saccharomyces cerevisiae. Mol Biol Cell 14(2):730-47 SGD PMID 12589066
- ↑ Radji M, et al. (2001) The cloning and characterization of the CDC50 gene family in Saccharomyces cerevisiae. Yeast 18(3):195-205 SGD PMID 11180453
- ↑ Saito K, et al. (2004) Cdc50p, a protein required for polarized growth, associates with the Drs2p P-type ATPase implicated in phospholipid translocation in Saccharomyces cerevisiae. Mol Biol Cell 15(7):3418-32 SGD PMID 15090616
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