YGR214W

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Systematic name YGR214W
Gene name RPS0A
Aliases NAB1, NAB1A, YST1
Feature type ORF, Verified
Coordinates Chr VII:920575..921788
Primary SGDID S000003446


Description of YGR214W: Ribosomal 40S subunit protein S0A; required for maturation of 18S rRNA along with Rps0Bp; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal; homologous to human ribosomal protein SA and bacterial S2; RPS0A has a paralog, RPS0B, that arose from the whole genome duplication;[1][2][3][4][5]




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References

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  1. Byrne KP and Wolfe KH (2005) The Yeast Gene Order Browser: combining curated homology and syntenic context reveals gene fate in polyploid species. Genome Res 15(10):1456-61 SGD PMID 16169922
  2. Demianova M, et al. (1996) Yeast proteins related to the p40/laminin receptor precursor are essential components of the 40 S ribosomal subunit. J Biol Chem 271(19):11383-91 SGD PMID 8626693
  3. Ford CL, et al. (1999) Yeast proteins related to the p40/laminin receptor precursor are required for 20S ribosomal RNA processing and the maturation of 40S ribosomal subunits. Cancer Res 59(3):704-10 SGD PMID 9973221
  4. Jenner L, et al. (2012) Crystal structure of the 80S yeast ribosome. Curr Opin Struct Biol () SGD PMID 22884264
  5. Lecompte O, et al. (2002) Comparative analysis of ribosomal proteins in complete genomes: an example of reductive evolution at the domain scale. Nucleic Acids Res 30(24):5382-90 SGD PMID 12490706

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