YJL208C

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Systematic name YJL208C
Gene name NUC1
Aliases
Feature type ORF, Verified
Coordinates Chr X:41183..40194


Description of YJL208C: Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has a role in mitochondrial recombination and in apoptosis[1][2][3][4]




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References

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  1. Buttner S, et al. (2007) Endonuclease g regulates budding yeast life and death. Mol Cell 25(2):233-46 SGD PMID 17244531
  2. Dake E, et al. (1988) Purification and properties of the major nuclease from mitochondria of Saccharomyces cerevisiae. J Biol Chem 263(16):7691-702 SGD PMID 3286639
  3. Zassenhaus HP and Denniger G (1994) Analysis of the role of the NUC1 endo/exonuclease in yeast mitochondrial DNA recombination. Curr Genet 25(2):142-9 SGD PMID 8087883
  4. Vincent RD, et al. (1988) Sequence and expression of NUC1, the gene encoding the mitochondrial nuclease in Saccharomyces cerevisiae. Nucleic Acids Res 16(8):3297-312 SGD PMID 2836792

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