YHR197W

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Systematic name YHR197W
Gene name RIX1
Aliases IPI2
Feature type ORF, Verified
Coordinates Chr VIII:493896..496187


Description of YHR197W: Essential component of the Rix1 complex (Rix1p, Ipi1p, Ipi3p) that is required for processing of ITS2 sequences from 35S pre-rRNA; Rix1 complex associates with Mdn1p in pre-60S ribosomal particles[1][2][3]




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References

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  1. Nissan TA, et al. (2004) A pre-ribosome with a tadpole-like structure functions in ATP-dependent maturation of 60S subunits. Mol Cell 15(2):295-301 SGD PMID 15260980
  2. Krogan NJ, et al. (2004) High-definition macromolecular composition of yeast RNA-processing complexes. Mol Cell 13(2):225-39 SGD PMID 14759368
  3. Gadal O, et al. (2001) Nuclear export of 60s ribosomal subunits depends on Xpo1p and requires a nuclear export sequence-containing factor, Nmd3p, that associates with the large subunit protein Rpl10p. Mol Cell Biol 21(10):3405-15 SGD PMID 11313466

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