YDL232W

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Systematic name YDL232W
Gene name OST4
Aliases
Feature type ORF, Verified
Coordinates Chr IV:38488..38598
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Description of YDL232W: Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes protein asparagine-linked glycosylation; type I membrane protein required for incorporation of Ost3p or Ost6p into the OST complex[1][2][3][4]



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References

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  1. Spirig U, et al. (2005) The 3.4-kDa Ost4 protein is required for the assembly of two distinct oligosaccharyltransferase complexes in yeast. Glycobiology 15(12):1396-406 SGD PMID 16096346
  2. Kim H, et al. (2003) Determination of the membrane topology of Ost4p and its subunit interactions in the oligosaccharyltransferase complex in Saccharomyces cerevisiae. Proc Natl Acad Sci U S A 100(13):7460-4 SGD PMID 12810948
  3. Knauer R and Lehle L (1999) The oligosaccharyltransferase complex from yeast. Biochim Biophys Acta 1426(2):259-73 SGD PMID 9878773
  4. Chi JH, et al. (1996) The OST4 gene of Saccharomyces cerevisiae encodes an unusually small protein required for normal levels of oligosaccharyltransferase activity. J Biol Chem 271(6):3132-40 SGD PMID 8621712

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