YLR208W
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| Systematic name | YLR208W |
| Gene name | SEC13 |
| Aliases | ANU3 |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:559551..560444 |
| Primary SGDID | S000004198 |
Description of YLR208W: Structural component of three distinct complexes; subunit of the Nup84 nuclear pore sub-complex (NPC), the COPII vesicle coat, and the Seh1-associated (SEA) complex; the COPII vesicle coat is required for vesicle formation in ER to Golgi transport; the Nup84 subcomplex contributes to nucleocytoplasmic transport, NPC biogenesis and processes that may require localization of genes or chromosomes at the nuclear periphery including transcription; homologous to human SEC13[1][2][3][4][5][6][7][8][9][10]
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References
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- ↑ Antonny B, et al. (2003) Self-assembly of minimal COPII cages. EMBO Rep 4(4):419-24 SGD PMID 12671686
- ↑ Barlowe C, et al. (1994) COPII: a membrane coat formed by Sec proteins that drive vesicle budding from the endoplasmic reticulum. Cell 77(6):895-907 SGD PMID 8004676
- ↑ Copic A, et al. (2012) ER Cargo Properties Specify a Requirement for COPII Coat Rigidity Mediated by Sec13p. Science () SGD PMID 22300850
- ↑ Dokudovskaya S, et al. (2011) A conserved coatomer-related complex containing Sec13 and Seh1 dynamically associates with the vacuole in Saccharomyces cerevisiae. Mol Cell Proteomics () SGD PMID 21454883
- ↑ Fernandez-Martinez J and Rout MP (2009) Nuclear pore complex biogenesis. Curr Opin Cell Biol 21(4):603-12 SGD PMID 19524430
- ↑ Lutzmann M, et al. (2002) Modular self-assembly of a Y-shaped multiprotein complex from seven nucleoporins. EMBO J 21(3):387-97 SGD PMID 11823431
- ↑ Menon BB, et al. (2005) Reverse recruitment: the Nup84 nuclear pore subcomplex mediates Rap1/Gcr1/Gcr2 transcriptional activation. Proc Natl Acad Sci U S A 102(16):5749-54 SGD PMID 15817685
- ↑ Pryer NK, et al. (1993) Cytosolic Sec13p complex is required for vesicle formation from the endoplasmic reticulum in vitro. J Cell Biol 120(4):865-75 SGD PMID 8432727
- ↑ Siniossoglou S, et al. (2000) Structure and assembly of the Nup84p complex. J Cell Biol 149(1):41-54 SGD PMID 10747086
- ↑ Tous C, et al. (2011) A novel assay identifies transcript elongation roles for the Nup84 complex and RNA processing factors. EMBO J 30(10):1953-64 SGD PMID 21478823
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