YPL147W
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| Systematic name | YPL147W |
| Gene name | PXA1 |
| Aliases | LPI1, PAL1, PAT2, SSH2 |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:273255..275867 |
| Primary SGDID | S000006068 |
Description of YPL147W: Subunit of a heterodimeric peroxisomal ATP-binding cassette transporter complex (Pxa1p-Pxa2p), required for import of long-chain fatty acids into peroxisomes; similarity to human adrenoleukodystrophy transporter ABCD1 and ABCD2 and ALD-related proteins; mutations in ABCD1 cause X-linked adrenoleukodystrophy (X-ALD), a peroxisomal disorder[1][2][3][4]
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Contents
Community Commentary
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DNA and RNA Details
Other DNA and RNA Details
Other Topic: expression
Specifically higher expression in carbon limited chemostat cultures versus carbon excess. [5] [6]
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References
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- ↑ Hettema EH, et al. (1996) The ABC transporter proteins Pat1 and Pat2 are required for import of long-chain fatty acids into peroxisomes of Saccharomyces cerevisiae. EMBO J 15(15):3813-22 SGD PMID 8670886
- ↑ Shani N and Valle D (1996) A Saccharomyces cerevisiae homolog of the human adrenoleukodystrophy transporter is a heterodimer of two half ATP-binding cassette transporters. Proc Natl Acad Sci U S A 93(21):11901-6 SGD PMID 8876235
- ↑ Shani N, et al. (1995) PXA1, a possible Saccharomyces cerevisiae ortholog of the human adrenoleukodystrophy gene. Proc Natl Acad Sci U S A 92(13):6012-6 SGD PMID 7597071
- ↑ Shani N, et al. (1996) An S. cerevisiae peroxisomal transporter, orthologous to the human adrenoleukodystrophy protein, appears to be a heterodimer of two half ABC transporters: Pxa1p and Pxa2p. Ann N Y Acad Sci 804:770-2 SGD PMID 8993619
- ↑ Boer VM, et al. (2003) The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. J Biol Chem 278(5):3265-74 SGD PMID 12414795
- ↑ submitted by Viktor Boer on 2003-07-25
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