YDR225W
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| Systematic name | YDR225W |
| Gene name | HTA1 |
| Aliases | H2A1, SPT11 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:915526..915924 |
Description of YDR225W: One of two nearly identical (see also HTA2) histone H2A subtypes; core histone required for chromatin assembly and chromosome function; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p [1][2][3][4][5]
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References
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- ↑ Song OK, et al. (2003) An Nalpha-acetyltransferase responsible for acetylation of the N-terminal residues of histones H4 and H2A. J Biol Chem 278(40):38109-12 SGD PMID 12915400
- ↑ Meeks-Wagner D and Hartwell LH (1986) Normal stoichiometry of histone dimer sets is necessary for high fidelity of mitotic chromosome transmission. Cell 44(1):43-52 SGD PMID 3510079
- ↑ Downs JA, et al. (2000) A role for Saccharomyces cerevisiae histone H2A in DNA repair. Nature 408(6815):1001-4 SGD PMID 11140636
- ↑ Choe J, et al. (1982) The two yeast histone H2A genes encode similar protein subtypes. Proc Natl Acad Sci U S A 79(5):1484-7 SGD PMID 7041122
- ↑ Norris D, et al. (1988) The effect of histone gene deletions on chromatin structure in Saccharomyces cerevisiae. Science 242(4879):759-61 SGD PMID 2847314
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