YDR009W

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Systematic name YDR009W
Gene name GAL3
Aliases
Feature type ORF, Verified
Coordinates Chr IV:463431..464993


Description of YDR009W: Transcriptional regulator involved in activation of the GAL genes in response to galactose; forms a complex with Gal80p to relieve Gal80p inhibition of Gal4p; binds galactose and ATP but does not have galactokinase activity[1][2][3]




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References

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  1. Timson DJ, et al. (2002) Gal3p and Gal1p interact with the transcriptional repressor Gal80p to form a complex of 1:1 stoichiometry. Biochem J 363(Pt 3):515-20 SGD PMID 11964151
  2. Bhat PJ and Murthy TV (2001) Transcriptional control of the GAL/MEL regulon of yeast Saccharomyces cerevisiae: mechanism of galactose-mediated signal transduction. Mol Microbiol 40(5):1059-66 SGD PMID 11401712
  3. Platt A and Reece RJ (1998) The yeast galactose genetic switch is mediated by the formation of a Gal4p-Gal80p-Gal3p complex. EMBO J 17(14):4086-91 SGD PMID 9670023

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