YHR207C

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Systematic name YHR207C
Gene name SET5
Aliases
Feature type ORF, Verified
Coordinates Chr VIII:516485..514905
Primary SGDID S000001250


Description of YHR207C: Methyltransferase involved in methylation of histone H4 Lys5, -8, -12; S-adenosylmethionine-dependent; zinc-finger protein, contains one canonical and two unusual fingers in unusual arrangements; deletion enhances replication of positive-strand RNA virus[1][2][3][4]




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References

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  1. Bohm S, et al. (1997) Variations of the C2H2 zinc finger motif in the yeast genome and classification of yeast zinc finger proteins. Nucleic Acids Res 25(12):2464-9 SGD PMID 9171100
  2. Green EM, et al. (2012) Methylation of H4 lysines 5, 8 and 12 by yeast Set5 calibrates chromatin stress responses.LID - 10.1038/nsmb.2252 [doi] Nat Struct Mol Biol () SGD PMID 22343720
  3. Kushner DB, et al. (2003) Systematic, genome-wide identification of host genes affecting replication of a positive-strand RNA virus. Proc Natl Acad Sci U S A 100(26):15764-9 SGD PMID 14671320
  4. Wlodarski T, et al. (2011) Comprehensive Structural and Substrate Specificity Classification of the Saccharomyces cerevisiae Methyltransferome. PLoS One 6(8):e23168 SGD PMID 21858014

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