YDL047W

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Systematic name YDL047W
Gene name SIT4
Aliases LGN4
Feature type ORF, Verified
Coordinates Chr IV:369769..370704
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Description of YDL047W: Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization[1][2][3][4][5]



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References

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  1. Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
  2. Angeles de la Torre-Ruiz M, et al. (2002) Sit4 is required for proper modulation of the biological functions mediated by Pkc1 and the cell integrity pathway in Saccharomyces cerevisiae. J Biol Chem 277(36):33468-76 SGD PMID 12080055
  3. Zabrocki P, et al. (2002) Protein phosphatase 2A on track for nutrient-induced signalling in yeast. Mol Microbiol 43(4):835-42 SGD PMID 11929536
  4. Sutton A, et al. (1991) The SIT4 protein phosphatase functions in late G1 for progression into S phase. Mol Cell Biol 11(4):2133-48 SGD PMID 1848673
  5. Stark MJ (1996) Yeast protein serine/threonine phosphatases: multiple roles and diverse regulation. Yeast 12(16):1647-75 SGD PMID 9123967

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