YPL262W
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| Systematic name | YPL262W |
| Gene name | FUM1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XVI:47336..48802 |
| Primary SGDID | S000006183 |
Description of YPL262W: Fumarase, converts fumaric acid to L-malic acid in the TCA cycle; cytosolic and mitochondrial distribution determined by the N-terminal targeting sequence, protein conformation, and status of glyoxylate shunt; phosphorylated in mitochondria[1][2][3][4]
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References
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- ↑ Przybyla-Zawislak B, et al. (1999) Genetic and biochemical interactions involving tricarboxylic acid cycle (TCA) function using a collection of mutants defective in all TCA cycle genes. Genetics 152(1):153-66 SGD PMID 10224250
- ↑ Regev-Rudzki N, et al. (2009) Dual localization of fumarase is dependent on the integrity of the glyoxylate shunt. Mol Microbiol 72(2):297-306 SGD PMID 19415796
- ↑ Reinders J, et al. (2007) Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase. Mol Cell Proteomics 6(11):1896-906 SGD PMID 17761666
- ↑ Sass E, et al. (2003) Folding of fumarase during mitochondrial import determines its dual targeting in yeast. J Biol Chem 278(46):45109-16 SGD PMID 12960177
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