YOR007C
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| Systematic name | YOR007C |
| Gene name | SGT2 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:339978..338938 |
| Primary SGDID | S000005533 |
Description of YOR007C: Glutamine-rich cytoplasmic protein that serves as a scaffold for binding Get4/5p and other proteins required to mediate posttranslational insertion of tail-anchored proteins into the ER membrane; has similarity to human cochaperone SGT[1][2][3][4]
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References
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- ↑ Angeletti PC, et al. (2002) Small glutamine-rich protein/viral protein U-binding protein is a novel cochaperone that affects heat shock protein 70 activity. Cell Stress Chaperones 7(3):258-68 SGD PMID 12482202
- ↑ Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 SGD PMID 14562095
- ↑ Kordes E, et al. (1998) Isolation and characterization of human SGT and identification of homologues in Saccharomyces cerevisiae and Caenorhabditis elegans. Genomics 52(1):90-4 SGD PMID 9740675
- ↑ Wang F, et al. (2010) A chaperone cascade sorts proteins for posttranslational membrane insertion into the endoplasmic reticulum. Mol Cell 40(1):159-71 SGD PMID 20850366
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