YOL112W
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Systematic name | YOL112W |
Gene name | MSB4 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr XV:106710..108188 |
Primary SGDID | S000005472 |
Description of YOL112W: GTPase-activating protein of the Ras superfamily that acts primarily on Sec4p, localizes to the bud site and bud tip, has similarity to Msb3p; msb3 msb4 double mutation causes defects in secretion and actin organization[1][2][3]
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References
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- ↑ Albert S and Gallwitz D (2000) Msb4p, a protein involved in Cdc42p-dependent organization of the actin cytoskeleton, is a Ypt/Rab-specific GAP. Biol Chem 381(5-6):453-6 SGD PMID 10937877
- ↑ Bi E, et al. (2000) Identification of novel, evolutionarily conserved Cdc42p-interacting proteins and of redundant pathways linking Cdc24p and Cdc42p to actin polarization in yeast. Mol Biol Cell 11(2):773-93 SGD PMID 10679030
- ↑ Gao XD, et al. (2003) The GAP activity of Msb3p and Msb4p for the Rab GTPase Sec4p is required for efficient exocytosis and actin organization. J Cell Biol 162(4):635-46 SGD PMID 12913108
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