YNL007C

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Systematic name YNL007C
Gene name SIS1
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:619565..618507
Primary SGDID S000004952


Description of YNL007C: Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p; not functionally redundant with Ydj1p due to due to substrate specificity; shares similarity with bacterial DnaJ proteins[1][2]




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References

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  1. Fan CY, et al. (2004) Exchangeable chaperone modules contribute to specification of type I and type II Hsp40 cellular function. Mol Biol Cell 15(2):761-73 SGD PMID 14657253
  2. Lu Z and Cyr DM (1998) Protein folding activity of Hsp70 is modified differentially by the hsp40 co-chaperones Sis1 and Ydj1. J Biol Chem 273(43):27824-30 SGD PMID 9774392

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