YMR049C

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Systematic name YMR049C
Gene name ERB1
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:370517..368094
Primary SGDID S000004652


Description of YMR049C: Constituent of 66S pre-ribosomal particles, forms a complex with Nop7p and Ytm1p that is required for maturation of the large ribosomal subunit; required for maturation of the 25S and 5.8S ribosomal RNAs; homologous to mammalian Bop1[1][2][3]




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References

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  1. Horsey EW, et al. (2004) Role of the yeast Rrp1 protein in the dynamics of pre-ribosome maturation. RNA 10(5):813-27 SGD PMID 15100437
  2. Miles TD, et al. (2005) Ytm1, Nop7, and Erb1 form a complex necessary for maturation of yeast 66S preribosomes. Mol Cell Biol 25(23):10419-32 SGD PMID 16287855
  3. Pestov DG, et al. (2001) ERB1, the yeast homolog of mammalian Bop1, is an essential gene required for maturation of the 25S and 5.8S ribosomal RNAs. Nucleic Acids Res 29(17):3621-30 SGD PMID 11522832

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