YLR205C
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| Systematic name | YLR205C |
| Gene name | HMX1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XII:553677..552724 |
| Primary SGDID | S000004195 |
Description of YLR205C: ER localized heme oxygenase, involved in heme degradation during iron starvation and in the oxidative stress response; expression is regulated by AFT1 and oxidative stress; relocates to the perinuclear region in the presence of oxidants[1][2][3][4][5]
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References
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- ↑ Auclair K, et al. (2003) Cloning and expression of a heme binding protein from the genome of Saccharomyces cerevisiae. Protein Expr Purif 28(2):340-9 SGD PMID 12699699
- ↑ Collinson EJ, et al. (2011) The Yeast Homolog of Heme Oxygenase-1 Affords Cellular Antioxidant Protection via the Transcriptional Regulation of Known Antioxidant Genes. J Biol Chem 286(3):2205-14 SGD PMID 21081499
- ↑ Foury F and Talibi D (2001) Mitochondrial control of iron homeostasis. A genome wide analysis of gene expression in a yeast frataxin-deficient strain. J Biol Chem 276(11):7762-8 SGD PMID 11112771
- ↑ Kim D, et al. (2006) Fungal heme oxygenases: Functional expression and characterization of Hmx1 from Saccharomyces cerevisiae and CaHmx1 from Candida albicans. Biochemistry 45(49):14772-80 SGD PMID 17144670
- ↑ Protchenko O and Philpott CC (2003) Regulation of intracellular heme levels by HMX1, a homologue of heme oxygenase, in Saccharomyces cerevisiae. J Biol Chem 278(38):36582-7 SGD PMID 12840010
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