YJL168C
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Systematic name | YJL168C |
Gene name | SET2 |
Aliases | EZL1 |
Feature type | ORF, Verified |
Coordinates | Chr X:104428..102227 |
Primary SGDID | S000003704 |
Description of YJL168C: Histone methyltransferase with a role in transcriptional elongation, methylates a lysine residue of histone H3; associates with the C-terminal domain of Rpo21p; histone methylation activity is regulated by phosphorylation status of Rpo21p[1][2][3][4]
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References
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- ↑ Li B, et al. (2003) The Set2 histone methyltransferase functions through the phosphorylated carboxyl-terminal domain of RNA polymerase II. J Biol Chem 278(11):8897-903 SGD PMID 12511561
- ↑ Schaft D, et al. (2003) The histone 3 lysine 36 methyltransferase, SET2, is involved in transcriptional elongation. Nucleic Acids Res 31(10):2475-82 SGD PMID 12736296
- ↑ Strahl BD, et al. (2002) Set2 is a nucleosomal histone H3-selective methyltransferase that mediates transcriptional repression. Mol Cell Biol 22(5):1298-306 SGD PMID 11839797
- ↑ Xiao T, et al. (2003) Phosphorylation of RNA polymerase II CTD regulates H3 methylation in yeast. Genes Dev 17(5):654-63 SGD PMID 12629047
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