YGL181W

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Systematic name YGL181W
Gene name GTS1
Aliases FHT1, LSR1
Feature type ORF, Verified
Coordinates Chr VII:157906..159096
Primary SGDID S000003149


Description of YGL181W: Protein involved in Arf3p regulation and in transcription regulation; localizes to the nucleus and to endocytic patches; contains an N-terminal Zn-finger and ArfGAP homology domain, a C-terminal glutamine-rich region, and a UBA (ubiquitin associated) domain; gts1 mutations affect budding, cell size, heat tolerance, sporulation, life span, ultradian rhythms, endocytosis; expression oscillates in a pattern similar to metabolic oscillations[1][2][3][4][5][6][7][8][9][10][11]




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References

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  1. Adams CA, et al. (2003) The Gts1 protein stabilizes the autonomous oscillator in yeast. Yeast 20(6):463-70 SGD PMID 12722180
  2. Bossier P, et al. (1997) Constitutive flocculation in Saccharomyces cerevisiae through overexpression of the GTS1 gene, coding for a 'Glo'-type Zn-finger-containing protein. Yeast 13(8):717-25 SGD PMID 9219336
  3. Mitsui K, et al. (1994) The GTS1 gene, which contains a Gly-Thr repeat, affects the timing of budding and cell size of the yeast Saccharomyces cerevisiae. Mol Cell Biol 14(8):5569-78 SGD PMID 8035831
  4. Saito T, et al. (2002) Regulation of the Gts1p level by the ubiquitination system to maintain metabolic oscillations in the continuous culture of yeast. J Biol Chem 277(37):33624-31 SGD PMID 12070147
  5. Shen H, et al. (2006) The mechanism by which overexpression of Gts1p induces flocculation in a FLO8-inactive strain of the yeast Saccharomyces cerevisiae. FEMS Yeast Res 6(6):914-23 SGD PMID 16911513
  6. Smaczynska-de Rooij II, et al. (2008) Yeast Arf3p Modulates Plasma Membrane PtdIns(4,5)P2 Levels to Facilitate Endocytosis. Traffic 9(4):559-73 SGD PMID 18208507
  7. Tonozuka H, et al. (2001) Analysis of the upstream regulatory region of the GTS1 gene required for its oscillatory expression. J Biochem 130(5):589-95 SGD PMID 11686920
  8. Toret CP, et al. (2008) Multiple pathways regulate endocytic coat disassembly in Saccharomyces cerevisiae for optimal downstream trafficking. Traffic 9(5):848-59 SGD PMID 18298676
  9. Xu Z and Tsurugi K (2007) Role of Gts1p in regulation of energy-metabolism oscillation in continuous cultures of the yeast Saccharomyces cerevisiae. Yeast 24(3):161-70 SGD PMID 17351907
  10. Yaguchi S, et al. (1996) The pleiotropic effect of the GTS1 gene product on heat tolerance, sporulation and the life span of Saccharomyces cerevisiae. Biochem Biophys Res Commun 218(1):234-7 SGD PMID 8573138
  11. Yaguchi S, et al. (2007) Localization of Gts1p in cortical actin patches of yeast and its possible role in endocytosis. Eur J Cell Biol 86(5):275-85 SGD PMID 17449140

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