YDR400W
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Systematic name | YDR400W |
Gene name | URH1 |
Aliases | |
Feature type | ORF, Verified |
Coordinates | Chr IV:1271063..1272085 |
Primary SGDID | S000002808 |
Description of YDR400W: Uridine nucleosidase (uridine-cytidine N-ribohydrolase), cleaves N-glycosidic bonds in nucleosides; involved in the pyrimidine salvage and nicotinamide riboside salvage pathways[1][2][3][4]
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References
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- ↑ Belenky P, et al. (2007) Nicotinamide riboside promotes Sir2 silencing and extends lifespan via Nrk and Urh1/Pnp1/Meu1 pathways to NAD+. Cell 129(3):473-84 SGD PMID 17482543
- ↑ Kurtz JE, et al. (1999) New insights into the pyrimidine salvage pathway of Saccharomyces cerevisiae: requirement of six genes for cytidine metabolism. Curr Genet 36(3):130-6 SGD PMID 10501935
- ↑ Kurtz JE, et al. (2002) The URH1 uridine ribohydrolase of Saccharomyces cerevisiae. Curr Genet 41(3):132-41 SGD PMID 12111094
- ↑ Mitterbauer R, et al. (2002) Saccharomyces cerevisiae URH1 (encoding uridine-cytidine N-ribohydrolase): functional complementation by a nucleoside hydrolase from a protozoan parasite and by a mammalian uridine phosphorylase. Appl Environ Microbiol 68(3):1336-43 SGD PMID 11872485
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