YDL209C
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| Systematic name | YDL209C |
| Gene name | CWC2 |
| Aliases | NTC40 |
| Feature type | ORF, Verified |
| Coordinates | Chr IV:87226..86207 |
| Primary SGDID | S000002368 |
Description of YDL209C: Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; binds directly to U6 snRNA; similar to S. pombe Cwf2[1][2][3]
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References
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- Jump up ↑ McGrail JC, et al. (2009) The RNA binding protein Cwc2 interacts directly with the U6 snRNA to link the nineteen complex to the spliceosome during pre-mRNA splicing. Nucleic Acids Res 37(13):4205-17 SGD PMID 19435883
- Jump up ↑ Ohi MD and Gould KL (2002) Characterization of interactions among the Cef1p-Prp19p-associated splicing complex. RNA 8(6):798-815 SGD PMID 12088152
- Jump up ↑ Ohi MD, et al. (2002) Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs. Mol Cell Biol 22(7):2011-24 SGD PMID 11884590
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