YPR019W

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Systematic name YPR019W
Gene name CDC54
Aliases HCD21, MCM4
Feature type ORF, Verified
Coordinates Chr XVI:596747..599548


Description of YPR019W: Essential helicase component of heterohexameric MCM2-7 complexes which bind pre-replication complexes on DNA and melt the DNA prior to replication; accumulates in the nucleus in G1; homolog of S. pombe Cdc21p[1][2]




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References

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  1. ↑ Tanaka S and Diffley JF (2002) Interdependent nuclear accumulation of budding yeast Cdt1 and Mcm2-7 during G1 phase. Nat Cell Biol 4(3):198-207 SGD PMID 11836525
  2. ↑ Tye BK (1999) MCM proteins in DNA replication. Annu Rev Biochem 68():649-86 SGD PMID 10872463

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