YPL128C

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Systematic name YPL128C
Gene name TBF1
Aliases LPI16
Feature type ORF, Verified
Coordinates Chr XVI:308220..306532


Description of YPL128C: Telobox-containing general regulatory factor; binds to TTAGGG repeats within subtelomeric anti-silencing regions (STARs) and possibly throughout the genome and mediates their insulating capacity by blocking silent chromatin propagation[1][2][3][4][5]




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References

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  1. Bilaud T, et al. (1996) The telobox, a Myb-related telomeric DNA binding motif found in proteins from yeast, plants and human. Nucleic Acids Res 24(7):1294-303 SGD PMID 8614633
  2. Fourel G, et al. (2002) General regulatory factors (GRFs) as genome partitioners. J Biol Chem 277(44):41736-43 SGD PMID 12200417
  3. Fourel G, et al. (2001) An activation-independent role of transcription factors in insulator function. EMBO Rep 2(2):124-32 SGD PMID 11258704
  4. Fourel G, et al. (1999) Cohabitation of insulators and silencing elements in yeast subtelomeric regions. EMBO J 18(9):2522-37 SGD PMID 10228166
  5. Koering CE, et al. (2000) Identification of high affinity Tbf1p-binding sites within the budding yeast genome. Nucleic Acids Res 28(13):2519-26 SGD PMID 10871401

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