YPL057C

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Systematic name YPL057C
Gene name SUR1
Aliases BCL21, CSG1, LPE15
Feature type ORF, Verified
Coordinates Chr XVI:453054..451906


Description of YPL057C: Probable catalytic subunit of a mannosylinositol phosphorylceramide (MIPC) synthase, forms a complex with probable regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Csh1p[1][2]




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References

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  1. Uemura S, et al. (2003) Csg1p and newly identified Csh1p function in mannosylinositol phosphorylceramide synthesis by interacting with Csg2p. J Biol Chem 278(46):45049-55 SGD PMID 12954640
  2. Beeler TJ, et al. (1997) SUR1 (CSG1/BCL21), a gene necessary for growth of Saccharomyces cerevisiae in the presence of high Ca2+ concentrations at 37 degrees C, is required for mannosylation of inositolphosphorylceramide. Mol Gen Genet 255(6):570-9 SGD PMID 9323360

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