YOR243C

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Systematic name YOR243C
Gene name PUS7
Aliases
Feature type ORF, Verified
Coordinates Chr XV:792242..790212


Description of YOR243C: Pseudouridine synthase, catalyzes pseudouridylation at position 35 in U2 snRNA, position 13 in cytoplasmic tRNAs, and position 35 in pre-tRNA(Tyr); Asp(256) mutation abolishes activity; conserved in archaea, some bacteria, and vertebrates[1]




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References

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  1. ↑ Behm-Ansmant I, et al. (2003) The Saccharomyces cerevisiae U2 snRNA:pseudouridine-synthase Pus7p is a novel multisite-multisubstrate RNA:Psi-synthase also acting on tRNAs. RNA 9(11):1371-82 SGD PMID 14561887

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