YOL026C
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| Systematic name | YOL026C |
| Gene name | MIM1 |
| Aliases | TOM13 |
| Feature type | ORF, Verified |
| Coordinates | Chr XV:274353..274012 |
| Primary SGDID | S000005386 |
Description of YOL026C: Mitochondrial protein required for outer membrane protein import; cooperates with Tom70p to import the subset of proteins with multiple alpha-helical transmembrane segments, including Ugo1p, Tom20p, and others; present as an oligomer in the outer membrane that may create a local environment that facilitates membrane insertion of substrate proteins; also has a role in assembly of Tom20p into the TOM complex[1][2][3][4][5][6][7]
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References
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- ↑ Becker T, et al. (2008) Biogenesis of the mitochondrial TOM complex: Mim1 promotes insertion and assembly of signal-anchored receptors. J Biol Chem 283(1):120-7 SGD PMID 17974559
- ↑ Becker T, et al. (2011) The mitochondrial import protein Mim1 promotes biogenesis of multispanning outer membrane proteins. J Cell Biol 194(3):387-95 SGD PMID 21825073
- ↑ Hulett JM, et al. (2008) The transmembrane segment of Tom20 is recognized by Mim1 for docking to the mitochondrial TOM complex. J Mol Biol 376(3):694-704 SGD PMID 18187149
- ↑ Ishikawa D, et al. (2004) Two novel proteins in the mitochondrial outer membrane mediate beta-barrel protein assembly. J Cell Biol 166(5):621-7 SGD PMID 15326197
- ↑ Mnaimneh S, et al. (2004) Exploration of essential gene functions via titratable promoter alleles. Cell 118(1):31-44 SGD PMID 15242642
- ↑ Papic D, et al. (2011) Multispan mitochondrial outer membrane protein Ugo1 follows a unique Mim1-dependent import pathway. J Cell Biol 194(3):397-405 SGD PMID 21825074
- ↑ Waizenegger T, et al. (2005) Mim1, a protein required for the assembly of the TOM complex of mitochondria. EMBO Rep 6(1):57-62 SGD PMID 15608614
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