YBR248C
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| Systematic name | YBR248C | |
| Gene name | HIS7 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr II:716460..714802 | |
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Description of YBR248C: Imidazole glycerol phosphate synthase (glutamine amidotransferase:cyclase), catalyzes the fifth and sixth steps of histidine biosynthesis and also produces 5-aminoimidazole-4-carboxamide ribotide (AICAR), a purine precursor[1][2][3]
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References
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- ↑ Alifano P, et al. (1996) Histidine biosynthetic pathway and genes: structure, regulation, and evolution. Microbiol Rev 60(1):44-69 SGD PMID 8852895
- ↑ Kuenzler M, et al. (1993) Cloning, primary structure, and regulation of the HIS7 gene encoding a bifunctional glutamine amidotransferase: cyclase from Saccharomyces cerevisiae. J Bacteriol 175(17):5548-58 SGD PMID 8366040
- ↑ Chittur SV, et al. (2000) Expression and purification of imidazole glycerol phosphate synthase from Saccharomyces cerevisiae. Protein Expr Purif 18(3):366-77 SGD PMID 10733892
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