YOR162C

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Systematic name YOR162C
Gene name YRR1
Aliases PDR2
Feature type ORF, Verified
Coordinates Chr XV:641993..639561


Description of YOR162C: Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrm1p, acting on an overlapping set of target genes[1][2][3][4]




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References

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  1. Lucau-Danila A, et al. (2003) Competitive promoter occupancy by two yeast paralogous transcription factors controlling the multidrug resistance phenomenon. J Biol Chem 278(52):52641-50 SGD PMID 14512416
  2. Le Crom S, et al. (2002) New insights into the pleiotropic drug resistance network from genome-wide characterization of the YRR1 transcription factor regulation system. Mol Cell Biol 22(8):2642-9 SGD PMID 11909958
  3. Zhang X, et al. (2001) Cross-talk between transcriptional regulators of multidrug resistance in Saccharomyces cerevisiae. J Biol Chem 276(12):8812-9 SGD PMID 11134057
  4. Cui Z, et al. (1998) Yeast gene YRR1, which is required for resistance to 4-nitroquinoline N-oxide, mediates transcriptional activation of the multidrug resistance transporter gene SNQ2. Mol Microbiol 29(5):1307-15 SGD PMID 9767597

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