YBR243C

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Systematic name YBR243C
Gene name ALG7
Aliases TUR1
Feature type ORF, Verified
Coordinates Chr II:706788..705442
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Description of YBR243C: UDP-N-acetyl-glucosamine-1-P transferase, transfers Glc-Nac-P from UDP-GlcNac to Dol-P in the ER in the first step of the dolichol pathway of protein asparagine-linked glycosylation; inhibited by tunicamycin[1][2]



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References

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  1. Barnes G, et al. (1984) Asparagine-linked glycosylation in Saccharomyces cerevisiae: genetic analysis of an early step. Mol Cell Biol 4(11):2381-8 SGD PMID 6096695
  2. Kukuruzinska MA and Lennon K (1995) Diminished activity of the first N-glycosylation enzyme, dolichol-P-dependent N-acetylglucosamine-1-P transferase (GPT), gives rise to mutant phenotypes in yeast. Biochim Biophys Acta 1247(1):51-9 SGD PMID 7873591

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