YOL002C

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Systematic name YOL002C
Gene name IZH2
Aliases PHO36
Feature type ORF, Verified
Coordinates Chr XV:324365..323412


Description of YOL002C: Plasma membrane protein involved in zinc metabolism and osmotin-induced apoptosis; transcription regulated by Zap1p, zinc and fatty acid levels; similar to mammalian adiponectins; deletion increases sensitivity to elevated zinc[1][2]




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References

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  1. Narasimhan ML, et al. (2005) Osmotin is a homolog of mammalian adiponectin and controls apoptosis in yeast through a homolog of mammalian adiponectin receptor. Mol Cell 17(2):171-80 SGD PMID 15664187
  2. Karpichev IV, et al. (2002) Multiple regulatory roles of a novel Saccharomyces cerevisiae protein, encoded by YOL002c, in lipid and phosphate metabolism. J Biol Chem 277(22):19609-17 SGD PMID 11916977

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