YNL131W

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Systematic name YNL131W
Gene name TOM22
Aliases MAS17, MAS22, MOM22
Feature type ORF, Verified
Coordinates Chr XIV:378769..379227


Description of YNL131W: Component of the TOM (translocase of outer membrane) complex responsible for initial import of mitochondrially directed proteins; acts as a receptor for precursor proteins and mediates interaction between the TOM and TIM complexes[1][2][3][4][5]




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References

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  1. Pfanner N, et al. (2004) Assembling the mitochondrial outer membrane. Nat Struct Mol Biol 11(11):1044-8 SGD PMID 15523480
  2. Chacinska A, et al. (2003) Mitochondrial translocation contact sites: separation of dynamic and stabilizing elements in formation of a TOM-TIM-preprotein supercomplex. EMBO J 22(20):5370-81 SGD PMID 14532110
  3. Ryan MT, et al. (2000) The transport machinery for the import of preproteins across the outer mitochondrial membrane. Int J Biochem Cell Biol 32(1):13-21 SGD PMID 10661891
  4. Meisinger C, et al. (1999) The preprotein translocase of the outer mitochondrial membrane: receptors and a general import pore. Cell Mol Life Sci 56(9-10):817-24 SGD PMID 11212341
  5. van Wilpe S, et al. (1999) Tom22 is a multifunctional organizer of the mitochondrial preprotein translocase. Nature 401(6752):485-9 SGD PMID 10519552

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