YBR186W
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| Systematic name | YBR186W | |
| Gene name | PCH2 | |
| Aliases | ||
| Feature type | ORF, Verified | |
| Coordinates | Chr II:600548..602355 | |
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Description of YBR186W: Nucleolar component of the pachytene checkpoint, which prevents chromosome segregation when recombination and chromosome synapsis are defective; also represses meiotic interhomolog recombination in the rDNA[1][2]
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References
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- Jump up ↑ San-Segundo PA and Roeder GS (2000) Role for the silencing protein Dot1 in meiotic checkpoint control. Mol Biol Cell 11(10):3601-15 SGD PMID 11029058
- Jump up ↑ San-Segundo PA and Roeder GS (1999) Pch2 links chromatin silencing to meiotic checkpoint control. Cell 97(3):313-24 SGD PMID 10319812
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