YNL082W

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Systematic name YNL082W
Gene name PMS1
Aliases
Feature type ORF, Verified
Coordinates Chr XIV:473392..476013


Description of YNL082W: ATP-binding protein required for mismatch repair in mitosis and meiosis; functions as a heterodimer with Mlh1p, binds double- and single-stranded DNA via its N-terminal domain, similar to E. coli MutL[1][2][3]




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References

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  1. Hall MC, et al. (2003) DNA binding by yeast Mlh1 and Pms1: implications for DNA mismatch repair. Nucleic Acids Res 31(8):2025-34 SGD PMID 12682353
  2. Hall MC, et al. (2002) Differential ATP binding and intrinsic ATP hydrolysis by amino-terminal domains of the yeast Mlh1 and Pms1 proteins. J Biol Chem 277(5):3673-9 SGD PMID 11717305
  3. Williamson MS, et al. (1985) Meiotic gene conversion mutants in Saccharomyces cerevisiae. I. Isolation and characterization of pms1-1 and pms1-2. Genetics 110(4):609-46 SGD PMID 3896926

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