YMR281W

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Systematic name YMR281W
Gene name GPI12
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:832338..833252


Description of YMR281W: ER membrane protein involved in the second step of glycosylphosphatidylinositol (GPI) anchor assembly, the de-N-acetylation of the N-acetylglucosaminylphosphatidylinositol intermediate; functional homolog of human PIG-Lp[1]




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References

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  1. ↑ Watanabe R, et al. (1999) Mammalian PIG-L and its yeast homologue Gpi12p are N-acetylglucosaminylphosphatidylinositol de-N-acetylases essential in glycosylphosphatidylinositol biosynthesis. Biochem J 339 ( Pt 1)():185-92 SGD PMID 10085243

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