YMR229C

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Systematic name YMR229C
Gene name RRP5
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:731122..725933


Description of YMR229C: Protein required for the synthesis of both 18S and 5.8S rRNA; C-terminal region is crucial for the formation of 18S rRNA and N-terminal region is required for the 5.8S rRNA; component of small ribosomal subunit (SSU) processosome[1][2][3][4]




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References

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  1. Osheim YN, et al. (2004) Pre-18S ribosomal RNA is structurally compacted into the SSU processome prior to being cleaved from nascent transcripts in Saccharomyces cerevisiae. Mol Cell 16(6):943-54 SGD PMID 15610737
  2. Fath S, et al. (2000) Association of yeast RNA polymerase I with a nucleolar substructure active in rRNA synthesis and processing. J Cell Biol 149(3):575-90 SGD PMID 10791972
  3. Venema J and Tollervey D (1996) RRP5 is required for formation of both 18S and 5.8S rRNA in yeast. EMBO J 15(20):5701-14 SGD PMID 8896463
  4. Eppens NA, et al. (1999) The roles of Rrp5p in the synthesis of yeast 18S and 5.8S rRNA can be functionally and physically separated. RNA 5(6):779-93 SGD PMID 10376877

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