YMR200W
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| Systematic name | YMR200W |
| Gene name | ROT1 |
| Aliases | |
| Feature type | ORF, Verified |
| Coordinates | Chr XIII:664751..665521 |
Description of YMR200W: Essential ER membrane protein; may be involved in protein folding; mutation causes defects in cell wall synthesis and in lysis of autophagic bodies, suppresses tor2 mutations, and is synthetically lethal with kar2-1 and with rot2 mutations[1][2][3]
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References
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- ↑ Takeuchi M, et al. (2006) Causal Links Between Protein Folding in the ER and Events Along the Secretory Pathway. Autophagy 2(4):323-4 SGD PMID 16874095
- ↑ Takeuchi M, et al. (2006) Saccharomyces cerevisiae Rot1p Is an ER-Localized Membrane Protein That May Function with BiP/Kar2p in Protein Folding. J Biochem (Tokyo) 139(3):597-605 SGD PMID 16567426
- ↑ Bickle M, et al. (1998) Cell wall integrity modulates RHO1 activity via the exchange factor ROM2. EMBO J 17(8):2235-45 SGD PMID 9545237
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