YMR153W

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Systematic name YMR153W
Gene name NUP53
Aliases
Feature type ORF, Verified
Coordinates Chr XIII:564434..565861


Description of YMR153W: Subunit of the nuclear pore complex (NPC), interacts with karyopherin Kap121p or with Nup170p via overlapping regions of Nup53p, involved in activation of the spindle checkpoint mediated by the Mad1p-Mad2p complex[1][2]




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References

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  1. Iouk T, et al. (2002) The yeast nuclear pore complex functionally interacts with components of the spindle assembly checkpoint. J Cell Biol 159(5):807-19 SGD PMID 12473689
  2. Lusk CP, et al. (2002) Karyopherins in nuclear pore biogenesis: a role for Kap121p in the assembly of Nup53p into nuclear pore complexes. J Cell Biol 159(2):267-78 SGD PMID 12403813

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